While osseointegration has traditionally been the focal point of dental implant design, recent research highlights the equally crucial role of establishing a resilient and biologically integrated soft tissue seal for long-term implant success. This review critically examines recent advances (primarily from the past five years) that elucidate the molecular, cellular, and materials science strategies essential […]
Cancer has become a major global health challenge, and current treatment modalities, including surgery, radiotherapy, chemotherapy, targeted therapy, and immunotherapy, all have inherent limitations. In recent years, nanotechnology, particularly carbon-based nanozymes, has emerged as a promising approach in cancer therapy. Carbon-based nanozymes, as a novel class of catalysts, offer excellent biocompatibility, low toxicity, and good […]
DNA methylation-based chronological age estimation is a powerful forensic tool, but its application to commonly encountered oral-derived samples (e.g., buccal swabs, saliva) is hampered by tissue specificity and inherent cellular heterogeneity, often leading to inaccurate predictions with existing models. This study aimed to overcome these limitations by developing and validating a robust cross-tissue DNA methylation […]