BVS Odontologia

Documentos Recientes

• Embryotoxicity and teratogenicity of the aqueous extract of Cinnamomum verum in zebrafish (Danio rerio): a concentration-dependent developmental toxicity assessment.
  ETHNOPHARMACOLOGICAL RELEVANCE: Cinnamomum verum has been extensively utilized in both traditional medicinal practices and culinary preparations. Nevertheless, its safety profile concerning embryonic development remains inadequately documented. AIM OF THE STUDY: This study aimed to evaluate the embryotoxic potential and teratogenic effects of the Cinnamomum verum aqueous extract using the zebrafish (Danio rerio) embryo model. MATERIALS […]
• Characterization of human airway-derived decellularized extracellulr matrix hydrogels and their effects on airway epithelial cell growth, organization and differentiation.
  Three-dimensional human airway models are useful tools to study respiratory development, disease and regeneration. However, commonly used substrates such as Matrigel™ differ substantially from native airway ECM, and effects on cell behavior remain incompletely characterized. Human airway-derived decellularized ECM (AW-dECM) hydrogels represent a potentially more physiological alternative, but their properties relative to conventional matrices are […]
• Lymph node-targeted mRNA delivery of fine-tuned peptide-nanocomplexes for SARS-CoV-2 Vaccination.
  Messenger RNA (mRNA) vaccines require efficient delivery systems to reach antigen-presenting cells (APCs). Lipid nanoparticles (LNPs) are a standard delivery carrier. However, LNPs often accumulate in the liver and exhibit transient protein expression. These limitations can restrict their safety and immunogenic potential. Here, we developed a modular, peptide-based nanocomplex to overcome the current limitations. The […]